The Department of Physiology is one of the departments established at the founding of the faculty itself in September 2006. Physiology is one of the fundamental sciences taught to medical students during the first two years of their academic programme to provide a comprehensive knowledge of the normal structure and function of the human body.

The Department of Physiology possess a fully equipped teaching laboratory for students and a state-of-the-art lung function testing equipment which include the only impulse oscillometry in a Sri Lankan state University.

The dedicated academic staff of the department includes six lecturers. The non-academic staff include two technical officers, a computer application assistant and two laboratory attendants are providing an invaluable service to the department.